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N-Acetyl-D-mannosamineN Acetyl D mannosamine (ManNAc) is an essential precursor of N acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA). N Acetyl D mannosamine (ManNAc) can be metabolized by GNE and GlcNAc 2 epimerase (Renin binding protein, RnBP), into ManNAc 6 phosphate and GlcNAc, respectively. N Acetyl d mannosamine (ManNAc) and its derivatives activates hypocretin (HCRT) gene expression in the orexin neurons, providing a
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N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA).N-Acetyl-D-mannosamine (ManNAc) can be metabolized by GNE and GlcNAc 2-epimerase (Renin binding protein, RnBP), into ManNAc-6-phosphate and GlcNAc, respectively. N-Acetyl-d-mannosamine (ManNAc) and its derivatives activates hypocretin (HCRT) gene expression in the orexin neurons, providing a potential model for the testing of a therapy for neural disorders.

Product information

CAS Number: 3615-17-6

Molecular Weight: 221.21

Formula: C8H15NO6

Chemical Name: N-[(2S, 3R, 4S, 5R)-3, 4, 5, 6-tetrahydroxy-1-oxohexan-2-yl]acetamide

Smiles: CC(=O)N[C@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO

InChiKey: MBLBDJOUHNCFQT-WCTZXXKLSA-N

InChi: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6-,7-,8-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 125 mg/mL (565.07 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

N-Acetyl-D-mannosamine

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