Recombinant Human IL-1α Protein

Sizes: 20μg, 100μg

Catalogue Numbers: PDMH100025-20, PDMH100025-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: IL-1α

Target Synonym: IL-1 alpha; Hematopoietin-1; IL1A; IL1F1; Interleukin-1 alpha; IL1a

UNIProt ID: P01583

Research Areas: Cancer; Cardiovascular; Immunology;

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

Accession: P01583

Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Sequence: Met1-Ala271

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 30.6 kDa

Observed MW: 35 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only