Ihh rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3753-50, ES3753-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015],

Alternate Name: IHH; Indian hedgehog protein; IHH; HHG-2

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Ihh. AA range:209-258

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 45kD

Human Gene ID: 3549

Human SWISS Prot NO: Q14623

Subcellular Location: [Indian hedgehog protein N-product]: Cell membrane; Lipid-anchor; Extracellular side. The N-terminal peptide remains associated with the cell surface.; [Indian hedgehog protein C-product]: Secreted, extracellular space. The C-terminal peptide diffuses from the cell.; Cell membrane.

Research Use Only