PCNA Monoclonal Antibody (12D10), AbFluor™ 680 Conjugated

Size: 50μL, 100μL

Catalogue Numbers: RA11816-50, RA11816-100

Citations, Manuals and MSDS Available upon request.

Background: proliferating cell nuclear antigen (PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.

Applications: WB; IF/ICC; IHC-p

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 5111

SWISS: P12004

Source: Mouse

Research Use Only