GAPDH Monoclonal Antibody (2B8), Biotin Conjugated

Size: 50μL, 100μL

Catalogue Numbers: RA11274-50, RA11274-100

Citations, Manuals and MSDS Available upon request.

Background: glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD) . The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferri

Condition: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications: WB; IF/ICC; IHC-p

Species Cross-Reactivity: Human; Rat; MouseMonkey; Dog; Hamster; Rabbit; Pig; sheep; Insect; Yeast

GeneID (Human): 2597

SWISS: P04406

Source: Mouse

Research Use Only